Skip to main content

Advertisement

Log in

Disease-syndrome combination clinical study of psoriasis: Present status, advantages, and prospects

  • Feature Article
  • Published:
Chinese Journal of Integrative Medicine Aims and scope Submit manuscript

Abstract

Psoriasis is an immune-abnormal, chronic, proliferative skin disease determined by polygenic inheritance and induced by a number of environmental factors. It causes worldwide concern because of its high-prevalence, harmful and incurable characteristics. Over the years, Chinese medicine (CM) treatment of psoriasis has accumulated a wealth of clinical experience. Disease-syndrome combination, which achieves more satisfactory clinical effect, is the basis to highlight the special CM advantages in treating psoriasis. In this paper, we review the advantages of treating psoriasis with the combination of disease and syndrome, analyze the prospects of research on treating psoriasis combining disease with syndrome. We also make a point that there are several key points for the clinical research of combination of disease and syndrome. It can be expected that carrying out clinical research on the combination of disease and syndrome will help improve the clinical efficacy of medical treatment of psoriasis, which will be the main direction of research in the future.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Raychaudhuri SP, Farber EM. The prevalence of psoriasis in the world. J Eur Acad Dermatol Venereol 2001;15:16–17.

    Article  PubMed  CAS  Google Scholar 

  2. Ding XL, Wang TL, Shen YW, Wang XY, Zhou C, Tian S, et al. Prevalence of psoriasis in China: an epidemiological survey in six provinces. Chin J Dermatol Venereol (Chin) 2010;24:598–601.

    Google Scholar 

  3. Alsufyani MA, Golant AK, Lebwohl M. Psoriasis and the metabolic syndrome. Dermetol Ther 2010;23:137–143.

    Article  Google Scholar 

  4. Cheng J, Yang XQ, Zhang L, Liu F, Hui RS, Wei LZ. Clinical characteristics of patients with psoriasis associated with metabolic syndrome. Med J Chin People Liberat Army (Chin) 2009;34:622–624.

    Google Scholar 

  5. Menter A, Gottlieb A, Feldman SR, van Voorhees AS, Leonardi CL, Gordon KB, et al. Guidelines of care for the management of psoriasis and psoriatic arthritis: section 1. Overview of psoriasis and guidelines of care for the treatment of psoriasis with biologics. J Am Acad Dermatol 2008;58:826–850.

    Article  PubMed  Google Scholar 

  6. Chen YJ, Wu CY, Chen TJ, Shen JL, Chu SY, Wang CB, et al. The risk of cancer in patients with psoriasis: a populationbased cohort study in Taiwan. J Am Acad Dermatol 2011;65:84–91.

    Article  PubMed  Google Scholar 

  7. Chen Z, Zhang JZ. Topical application of psoriasis vulgaris. Chin J Drug Applicat Monitor (Chin) 2005;1(5):34–37.

    Google Scholar 

  8. Puig L, Bordas X, Carrascosa JM, Daudén E, Ferrándiz C, Hernanz JM, et al. Consensus document on the evaluation and treatment of moderate to severe psoriasis. Spanish Psoriasis Group of the Spanish Academy of Dermatology and Venereology. Actas Dermosifiliogr 2009;100:277–286

    Article  PubMed  CAS  Google Scholar 

  9. Tang W, Zhou M, Lei YM. The methodological quality evaluation of the randomized controlled trial of the traditional Chinese meicine treatment on psoriasis. Liaoning J Tradit Chin Med (Chin) 2006;33:1066–1067.

    Google Scholar 

  10. Zhang JW, Wang JZ, Zhang H, Pang CK, Liu CX. The evidence-based evaluation of the randomized controlled trials of Chinese herbal treatment of the psoriasis vulgaris. China J Leprosy Skin Dis (Chin) 2003;19:370–372.

    CAS  Google Scholar 

  11. Ma KY. Clinical study of treating psoriasis of heat in blood system with Xiaoyin Pills. Modern Tradit Chin Med (Chin) 2003;23(4):8–9.

    Google Scholar 

  12. Liu J, Cha XS. Clinical observation of 32 patients with progressive psoriasis vulgaris of heat in blood system treated with Liangxue Xiaoyin Decoction. J New Chin Med (Chin) 2006;38(8):28–29.

    CAS  Google Scholar 

  13. Yan ZF, Song P, Liu WL. Clinical observation on Xiaoyin Ointment for the treatment of blood-heat syndrome of psoriasis. J Tradit Chin Med (Chin) 2008;49:225–227.

    Google Scholar 

  14. Cao HX, Wang YY, eds. Evidence-based guidelines of clinical practice in Chinese medicine. 1st ed. Beijing: China Press of Taditional Chinese Medicine; 2011:51–52.

    Google Scholar 

  15. Zhang W, Wang P. Observation on effects of progressive psoriasis vulgaris treated with Liangxue Jiedu Decoction. Modern J Integr Tradit Chin West Med (Chin) 2007;16:764.

    Google Scholar 

  16. Hu R, Yu WQ, Wang WC. Clinical observation of 30 patients with progressive psoriasis vulgaris treated with Liangxue Jiedu Xiaopi Decoctions. Jiangsu J Tradit Chin Med (Chin) 2008;40(4):41.

    CAS  Google Scholar 

  17. Yu B. The treatment of psoriasis vulgaris with Jiedu Xiaoyin Decoction. J Med Forum (Chin) 2008;29(19):87.

    CAS  Google Scholar 

  18. Li FL, Li B, Xu R, Song X, Yu Y, Xu ZC. Qinzhu Liangxue Decoction in treatment of blood-heat type psoriasis vulgaris: a randomized controlled trial. J Chin Integr Med (Chin) 2008;6:586.

    Article  Google Scholar 

  19. Xie SQ, Yi XM, Yang LJ, Li YP. Clinical observation of Kangyin 1 Decoction on 41 cases of psoriasis vulgaris. Hebei J Tradit Chin Med (Chin) 2009;3:173.

    Google Scholar 

  20. Hou LJ. Clinical observation of progressive psoriasis vulgaris treated with modifed Liangxue Huoxue Decoction. J Liaoning Univ Tradit Chin Med (Chin) 2009;16(11):132–133.

    Google Scholar 

  21. Tang DS, Xu JT. Observation of 32 cases of progressive psoriasis vulgaris treated with Liangxue Jiedu Decoction. J New Chin Med (Chin) 2009;41(5):77.

    Google Scholar 

  22. Ta L, Li JH, Cui XM, Pang XW, Zhou JS, Chen XR. Observation of 30 cases on psoriasis of blood stasis treated with Huayu Xiaoyin Granule. Chin J Pract Med (Chin) 2009;36(16):75–76.

    Article  Google Scholar 

  23. Jing SQ, Pei ZF, Qiao SH, Li ZL. Observation of 45 patients with psoriasis vulgaris of qi and blood stasis treated with activating blood circulation method. J Shaanxi Coll Tradit Chin Med (Chin) 2010;33(2):39.

    Google Scholar 

  24. Zhou M, Chen HR, Tao LC. Treatment of 30 cases of psoriasis vulgaris with Xuefuzhuyu Decoction. J Beijing Univ Tradit Chin Med (Chin) 2005;12(5):14.

    Google Scholar 

  25. Sun YL. Treatment of 125 cases of psoriasis vulgaris with method of activating blood circulation method. Hunan J Tradit Chin Med (Chin) 2007;23(5):58.

    Google Scholar 

  26. Zhang ZB. Treatment of psoriasis of blood stasis type with Jiawei Taohong Siwu Decoction. Shanxi J Tradit Chin Med (Chin) 2008;24(11):60.

    Google Scholar 

  27. Chen L. Clinical effect on treatment of 40 cases of psoriasis by Taohong Siwu Decoction. Guangming J Chin Med (Chin) 2009;24:1078.

    Google Scholar 

  28. Sun LP, Liu BM. Clinical observation of psoriasis vulgaris treated with Jiajian Siwu Decoction. Sichuan J Tradit Chin Med (Chin) 2009;27(5):101.

    Google Scholar 

  29. Jia LM, Wang XJ. Clinical observation of 192 patients with psoriasis vulgaris of blood deficiency and wind-dry type treated with Xiaoxieling Unguent. Heilongjiang J Tradit Chin Med (Chin) 2007;49(4):13–14.

    Google Scholar 

  30. Zhong JB, Li YQ, He WQ, Li YH, Liang YM. Clinical observation of treating psoriasis of blood deficiency and wind-dry type with Xiaoyin Granule in 60 cases. Gansu J Tradit Chin Med (Chin) 2008;21(11):28–29.

    Google Scholar 

  31. Yu HJ, Liu JZ. Experience on treatment of psoriasis with modifed Jingfang Siwu Decoction. J Labour Med (Chin) 2001;18:251.

    Google Scholar 

  32. Zhou DM, Wang P, Jiang CY, Chen WW, Wang LS. Clinical observation of psoriasis vulgaris treated from the view of blood. Beijing J Tradit Chin Med (Chin) 2009;28:435.

    Google Scholar 

  33. Deng BX, Jiang CY, Wang P, Liu WL, Qu X, Zhao YM, et al. Rule of distribution and development of TCM syndromes of psoriasis. J Tradit Chin Med (Chin) 2006;47:770–772.

    Google Scholar 

  34. Zhang GZ, Wang P, Wang LS, Jiang CY, Deng BX, Li P, et al. Study on the distribution and development rules of TCM syndromes of 2651 psoriasis vulgaris cases. J Tradit Chin Med (Chin) 2008;49:894–896.

    Google Scholar 

  35. Li TH, Qu X. Study on the rule of distribution of TCM syndromes of psoriasis. J Tradit Chin Med (Chin) 2010;51:544–546.

    Google Scholar 

  36. Gan J, Xie GL, Shi Y. Clinical oberservation of 48 psoriasis patients treated with combination of Chinese medicine and Western medicine. Guid J Tradit Chin Med Pharm (Chin) 2008;14(7):64.

    Google Scholar 

  37. Sun ZX, Wang JJ, Zhang FC, Li YQ, Li YW. The analysis of contemporary famous doctors’ experiences on the treatment of psoriasis. J Beijing Univ Tradit Chin Med (Chin) 2011;18:27–30.

    Google Scholar 

  38. Bronsard V, Paul C, Prey S, Puzenat E, Gourraud PA, Aractingi S, et al. What are the best outcome measures for assessing quality of life in plaque type psoriasis? A systematic review of the literature. J Europ Acad Dermatol Venereol 2010;24;17–22.

    Article  Google Scholar 

  39. García-Diez A, Foraster CF, Sebastián FV, Tudela LL, Llach XB, Fernández GS. What characterizes the severity of psoriasis? Dermatology 2008;216:137–15

    Article  PubMed  Google Scholar 

  40. He Z, Lu C, Basra MK, Ou A, Yan Y, Li L. Psychometric properties of the Chinese version of Dermatology Life Quality Index (DLQI) in 851 Chinese patients with psoriasis. J Eur Acad Dermatol Venereol. Doi:10.1111/j.1468-3083.2011.04371.x.

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Chuan-jian Lu  (卢传坚).

Additional information

Supported by the Financial Industry Technology Research and Development Program of Guangdong Province (No. 201105)

Rights and permissions

Reprints and permissions

About this article

Cite this article

Lu, Cj., Yu, Jj. & Deng, Jw. Disease-syndrome combination clinical study of psoriasis: Present status, advantages, and prospects. Chin. J. Integr. Med. 18, 166–171 (2012). https://doi.org/10.1007/s11655-012-1006-1

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11655-012-1006-1

Keywords

Navigation