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A New Hopantenic Acid Derivative from the Rhizomes of Heterosmilax japonica

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A new hopantenic acid derivative, (R)-methyl-4-(2,4-dihydroxy-3,3-dimethylbutanamido)butanoate (1), was isolated from the rhizomes of Heterosmilax japonica Kunth, together with three known compounds, (3S)-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid (2), daucosterol (3), and ethyl-β-D-xylobioside (4). The structure of 1 was determined by extensive spectroscopic analyses, including 1D and 2D NMR and HR-ESI-MS. Compounds 2 and 4 are new for the genus Heterosmilax.

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Acknowledgment

This work was financial supported by Science and Technology Program of Guangzhou, China (No. 201607010147).

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Authors and Affiliations

  1. School of Chinese Medicine, Guangdong Pharmaceutical University, 510006, Guangzhou, P. R. China

    Zhen Zhang, Chao-Zhi Chen, Xi-Feng Teng & Shu-Yuan Li

  2. School of Pharmaceutical Sciences, Southern Medical University, 510515, Guangzhou, P. R. China

    Li-Wen Tian

Authors
  1. Zhen Zhang
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  2. Chao-Zhi Chen
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  3. Xi-Feng Teng
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  4. Shu-Yuan Li
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Corresponding authors

Correspondence to Shu-Yuan Li or Li-Wen Tian.

Additional information

Published in Khimiya Prirodnykh Soedinenii, No. 6, November–December, 2018, pp. 953–954.

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Zhang, Z., Chen, CZ., Teng, XF. et al. A New Hopantenic Acid Derivative from the Rhizomes of Heterosmilax japonica. Chem Nat Compd 54, 1121–1122 (2018). https://doi.org/10.1007/s10600-018-2569-7

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  • DOI: https://doi.org/10.1007/s10600-018-2569-7

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