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Antimicrobial glycoalkaloids from the tubers of Stephania succifera

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Abstract

Three new glycoalkaloids, N-formyl-asimilobine-2-O-β-d-glucoside (1), (−)-1-O-β-d-glucoside-8-oxotetrahydropalmatine (2), and 1-N-monomethylcarbamate-argentinine-3-O-β-d-glucoside (3) were isolated from tubers of Stephania succifera. The structures were established based on spectroscopic analysis, and the antimicrobial activities of the three glycoalkaloids are reported.

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Acknowledgments

This research was financially supported by Special Fund for Agro-scientific Research in the Public Interest (201303117), and National Support Science and Technology Subject (2013BAI11B04).

Conflict of interest

All authors declare no conflict of interest.

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Authors and Affiliations

  1. Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, 571101, China

    Yan-Bo Zeng, Dai-Jing Wei, Wen-Hua Dong, Cai-Hong Cai, De-Lan Yang, Wen-Li Mei & Hao-Fu Dai

  2. College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao, 266042, China

    Dai-Jing Wei & Hui-Min Zhong

Authors
  1. Yan-Bo Zeng
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  2. Dai-Jing Wei
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  3. Wen-Hua Dong
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  4. Cai-Hong Cai
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  5. De-Lan Yang
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  6. Hui-Min Zhong
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  7. Wen-Li Mei
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  8. Hao-Fu Dai
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Corresponding authors

Correspondence to Wen-Li Mei or Hao-Fu Dai.

Additional information

Yan-Bo Zeng and Dai-Jing Wei have contributed equally to this study.

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Zeng, YB., Wei, DJ., Dong, WH. et al. Antimicrobial glycoalkaloids from the tubers of Stephania succifera . Arch. Pharm. Res. 40, 429–434 (2017). https://doi.org/10.1007/s12272-014-0467-5

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  • DOI: https://doi.org/10.1007/s12272-014-0467-5

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