A New Type of Colored Alumina/Glass Composite Biological Safety Assessment – Cell Toxicity and Hemolysis Tests

Bin Deng; Huai Xiu Lu; Long Quan Shao; Yuan Fu Yi; Jie Liu; Kang Lin Hou; Wei Wei Zhang; Ning Wen

doi:10.4028/www.scientific.net/AMR.177.459

Paper Titles

Effect of Heat-Pressing on the Microstructure and Properties of a Novel Lithium Disilicate Glass-Ceramic
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Crystal Phase Formation and Mechanical Properties of Lithium Disilicate Glass-Ceramics for Dental Restoration
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Indentation Fatigue and In Situ Inspection of Damage Evolution for Glass
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Testing and Evaluation of Infrared Radiation Property of Cordierite Based Glass-Ceramic Materials
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A New Type of Colored Alumina/Glass Composite Biological Safety Assessment – Cell Toxicity and Hemolysis Tests
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A New Type of Colored Alumina/Glass Composite Biological Safety Assessment - Oral Mucous Membrane Irritation and Skin Sensitivity Tests
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Corrosion Behaviors of Borosilicate Glasses in Various Leaching Agents
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Comparison of Leaching Characteristics of Lead in Waste CRTs
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Determination of Silicon-Carbide Content in 95 Silicon-Carbide Brick
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HomeAdvanced Materials ResearchAdvanced Materials Research Vol. 177A New Type of Colored Alumina/Glass Composite...

A New Type of Colored Alumina/Glass Composite Biological Safety Assessment – Cell Toxicity and Hemolysis Tests

Abstract:

Objective: to evaluate the biological safety of a colored alumina/glass composite in terms of cytotoxicity and hemolytic ability. Methods: the cytotoxicity of an alumina/glass composite was evaluated with molecular filtration method. Cytotoxicity by spectrophotometric responses of test material and responses of a fresh rabbit red blood anticoagulant solution was determined by spectrophotometer. Results: cell-coated filter paper in contact with the test material showed the appearance of intracellular blue dye as the same staining density as in control samples, leading to a toxicity rating of 0. Colored alumina/glass composite assayed at <5% hemolysis. Conclusion: colored alumina/glass composite materials showed low cytotoxicity and non-acute hemolytic rates, representing overall good biological safety under these conditions.

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Periodical:

Advanced Materials Research (Volume 177)

Pages:

459-461

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.177.459

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Online since:

December 2010

Authors:

Bin Deng, Huai Xiu Lu, Long Quan Shao, Yuan Fu Yi, Jie Liu, Kang Lin Hou, Wei Wei Zhang, Ning Wen

Keywords:

Alumina Glass Composite, Cell Toxicity Test, Hemolysis Test

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